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Warm-Up: Genetic Review 2

Multiple Choice: DARKEN the letter that best completes the statement or answers the question.
 
 
The pedigree below shows a family’s pedigree for Huntington’s disease.
nar001-1.jpg
 

 1. 
Which family members are afflicted with Huntington’s disease?
A
I-1, II-2, II-3, II-7, III-3
B
I-2, II-1, II-4, II-6, II-8
C
II-2, II-3, III-1
D
II-3, II-7, II-8, III-4
 

 2. 
There are no carriers for Huntington’s disease. You either have it or you don’t. With this in mind, what type of inheritance does Huntington’s disease follow?
A
autosomal recessive
C
sex-linked
B
autosomal dominant
D
codominant
 

 3. 
How many children did individuals I-1 and I-2 have?
A
2
C
4
E
6
B
3
D
5
 

 4. 
How many girls did II-1 and II-2 have? How many are affected?
A
2 girls, none with Huntington’s disease
B
2 girls, one with Huntington’s disease
C
3 girls, two with Huntington’s disease
D
3 girls, one with Huntington’s disease
E
3 girls, all with Huntington’s disease
 

 5. 
How are individuals III-2 and II-4 related?
A
daughter and mother
B
nephew and aunt
C
grandson and grandfather
D
niece and uncle
E
granddaughter and grandfather
 

 6. 
How are individuals I-2 and III-5 related?
A
grandma and granddaughter
D
father and daughter
B
grandma and grandson
E
mother and daughter
C
mother and son
 

 7. 
How many children did individuals I-1 and I-2 have?
A
3
D
6
B
4
E
7
C
5
 
 
The pedigree below shows a family’s pedigree for colorblindness:
nar002-1.jpg
 

 8. 
Which sex can be carriers of colorblindness and not have it?
A
females
B
males
 

 9. 
What kind of trait is colorblindness?
A
autosomal dominant
D
codominant
B
autosomal recessive
E
sex-linked recessive
C
sex-linked dominant
 

 10. 
What is the genotype of individual IV-7?
A
XbXb
D
XBXb
B
XbY
E
XBXB
C
XBY
 

 11. 
All of the following statements about colorblindness are true, EXCEPT:
A
Males are usually more severely affected than females. The trait may be lethal in males.
B
Parents of affected children may be related. The rarer the trait in the general population, the more likely a consanguineous mating is involved.
C
All sons of an affected male and a normal female are normal. All daughters of an affected male and a normal female are affected.
D
The trait is never passed from father to son.
E
Matings of affected females and normal males produce 1/2 the sons affected and 1/2 the daughters affected.
 

 12. 
Why do all the daughters in generation II carry the colorblind gene?
A
Their mother is a carrier with the Xb gene
B
Their dad is affected with only Xb gene to give to them
C
Their dad is homozygous dominant for the disorder
D
Their mom is homozygous recessive for the disorder
E
Their mom is heterozygous for the disorder
 

 13. 
Name two fourth generation colorblind males.
A
IV-1 and IV-7
D
IV-3 and Iv-6
B
IV-5 and IV-7
E
IV-1 and IV-5
C
IV-1 and IV-3
 
 
In the pedigree below, different blood types are identified by the letters A, B, AB, and O.
nar003-1.jpg
 

 14. 
Individuals II-4 and II-5 have just had identical twin girls. List the possible blood types these infants may have based on the information provided in the pedigree
A
Types A, B, AB and O
D
Types A and AB
B
Types A and B
E
Type O
C
Types B and AB
 

 15. 
Individuals II-6 and II-7 have a second child with blood type O. What does this tell you about II-6’s genotype?
A
IBi
D
IAIA
B
IBIB
E
ii
C
IAi
 

 16. 
Could I-1 and I-2 have a child with the AB blood type?
A
yes
B
no
 

 17. 
Which member of the family can only get blood from a type O donor?
A
I-2
D
I-4, II-3, II-4, II-6
B
I-3, II-1, II-2, II-5
E
the twins
C
I-1 and II-7
 

 18. 
Which blood type can receive from type A, B, AB and O?
A
type A
C
type AB
B
type B
D
type O
 

Short Answer
 
 
Use the exhibit to answer the questions that follow.
nar004-1.jpg
 

 19. 
What type of chart is shown in Figure 7.4?
 

 20. 
What do the shaded shapes represent?
 

 21. 
The phenotype is caused by a dominant allele. Write two statements to support this fact.
 

 22. 
The phenotype is caused by an autosomal gene. Explain why.
 

 23. 
Make a Punnett square using the parental genotypes. Find all the possible genotypes for the offspring in the F generation.
 



 
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